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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ADCY6 All Species: 22.12
Human Site: S608 Identified Species: 48.67
UniProt: O43306 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O43306 NP_056085.1 1168 130615 S608 Q M G I D D S S K D N R G T Q
Chimpanzee Pan troglodytes XP_509033 1166 130086 S606 Q M G I D D S S K D N R G T Q
Rhesus Macaque Macaca mulatta XP_001102486 1168 130543 S608 Q M G I D D S S K D N R G T Q
Dog Lupus familis XP_534819 1166 130415 S606 Q M G I D D S S K D N R G A Q
Cat Felis silvestris
Mouse Mus musculus Q01341 1165 130300 S605 Q M G I D D S S K D N R G A Q
Rat Rattus norvegicus Q03343 1166 130488 S606 Q M G I D D S S K E N R G A Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511957 593 65761 R82 D L E K K Y S R K V D S R F G
Chicken Gallus gallus Q9DGG6 1334 149273 K645 D E H K N S T K A P G G H S P
Frog Xenopus laevis P98999 1305 145393 G645 V S A A N G G G E E W K G G A
Zebra Danio Brachydanio rerio XP_002666536 1123 127693 W592 S E G L M P R W V P D R S F S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_001122246 1014 113539 Y503 I D Q L R T Q Y C T P F I L T
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 96.6 98.9 96.4 N.A. 94.1 93.3 N.A. 42.6 25.6 25.5 69.7 N.A. N.A. 43.4 N.A. N.A.
Protein Similarity: 100 97.2 99.5 97.5 N.A. 96 95.8 N.A. 45.6 41.5 42 79.4 N.A. N.A. 59.7 N.A. N.A.
P-Site Identity: 100 100 100 93.3 N.A. 93.3 86.6 N.A. 13.3 0 6.6 13.3 N.A. N.A. 0 N.A. N.A.
P-Site Similarity: 100 100 100 93.3 N.A. 93.3 93.3 N.A. 26.6 20 33.3 26.6 N.A. N.A. 6.6 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 10 10 0 0 0 0 10 0 0 0 0 28 10 % A
% Cys: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % C
% Asp: 19 10 0 0 55 55 0 0 0 46 19 0 0 0 0 % D
% Glu: 0 19 10 0 0 0 0 0 10 19 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 10 0 19 0 % F
% Gly: 0 0 64 0 0 10 10 10 0 0 10 10 64 10 10 % G
% His: 0 0 10 0 0 0 0 0 0 0 0 0 10 0 0 % H
% Ile: 10 0 0 55 0 0 0 0 0 0 0 0 10 0 0 % I
% Lys: 0 0 0 19 10 0 0 10 64 0 0 10 0 0 0 % K
% Leu: 0 10 0 19 0 0 0 0 0 0 0 0 0 10 0 % L
% Met: 0 55 0 0 10 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 19 0 0 0 0 0 55 0 0 0 0 % N
% Pro: 0 0 0 0 0 10 0 0 0 19 10 0 0 0 10 % P
% Gln: 55 0 10 0 0 0 10 0 0 0 0 0 0 0 55 % Q
% Arg: 0 0 0 0 10 0 10 10 0 0 0 64 10 0 0 % R
% Ser: 10 10 0 0 0 10 64 55 0 0 0 10 10 10 10 % S
% Thr: 0 0 0 0 0 10 10 0 0 10 0 0 0 28 10 % T
% Val: 10 0 0 0 0 0 0 0 10 10 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 10 0 0 10 0 0 0 0 % W
% Tyr: 0 0 0 0 0 10 0 10 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _